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Placebo effect requires your ‘permission’ to work

Placebo effect requires your ‘permission’ to work

April 29, 2026, 12:56 PM - 9 min read

Placebo treatments can trigger measurable changes in the brain, immune system and hormone function. In studies on pain, placebos cause the brain to release endorphins, the body’s natural opioids. In Parkinson’s disease, placebo injections increase dopamine activity in the brain. The placebo effect isn’t magic. It’s biology.

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